Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set01_ATM_minus_versus_ATM_plus |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | NCI_IL12-MEDIATED SIGNALING EVENTS |
| Enrichment Score (ES) | -0.59105617 |
| Normalized Enrichment Score (NES) | -2.2464747 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RAN | 122 | 13.946 | 0.0201 | No | ||
| 2 | GZMA | 588 | 8.487 | 0.0145 | No | ||
| 3 | IL12RB2 | 900 | 7.206 | 0.0135 | No | ||
| 4 | B2M | 1252 | 6.149 | 0.0088 | No | ||
| 5 | XPO1 | 1342 | 5.926 | 0.0156 | No | ||
| 6 | PIAS2 | 1349 | 5.909 | 0.0262 | No | ||
| 7 | IL2RB | 1434 | 5.742 | 0.0330 | No | ||
| 8 | UBE2D3 | 2039 | 4.762 | 0.0141 | No | ||
| 9 | ETV5 | 2349 | 4.365 | 0.0080 | No | ||
| 10 | CCL3 | 3147 | 3.696 | -0.0217 | No | ||
| 11 | IL2RA | 3564 | 3.387 | -0.0345 | No | ||
| 12 | MAP2K3 | 4337 | 2.980 | -0.0643 | No | ||
| 13 | IL18RAP | 6137 | 2.355 | -0.1423 | No | ||
| 14 | CD86 | 6218 | 2.331 | -0.1417 | No | ||
| 15 | PIK3R1 | 6230 | 2.327 | -0.1379 | No | ||
| 16 | IFNG | 6243 | 2.320 | -0.1342 | No | ||
| 17 | IL12A | 6521 | 2.246 | -0.1427 | No | ||
| 18 | CCR5 | 6663 | 2.205 | -0.1451 | No | ||
| 19 | NFKB1 | 7091 | 2.093 | -0.1608 | No | ||
| 20 | FASLG | 7259 | 2.047 | -0.1646 | No | ||
| 21 | IL17A | 7630 | 1.955 | -0.1780 | No | ||
| 22 | EOMES | 9639 | 1.476 | -0.2672 | No | ||
| 23 | IL18 | 9781 | 1.438 | -0.2710 | No | ||
| 24 | CCL4 | 10495 | 1.263 | -0.3013 | No | ||
| 25 | IL4 | 12402 | 0.724 | -0.3872 | No | ||
| 26 | JUN | 12565 | 0.666 | -0.3934 | No | ||
| 27 | IL12B | 12666 | 0.637 | -0.3968 | No | ||
| 28 | TBX21 | 13363 | 0.371 | -0.4280 | No | ||
| 29 | IL13 | 13554 | 0.294 | -0.4361 | No | ||
| 30 | IL6 | 13644 | 0.251 | -0.4397 | No | ||
| 31 | GADD45G | 13718 | 0.218 | -0.4427 | No | ||
| 32 | GZMB | 13821 | 0.160 | -0.4470 | No | ||
| 33 | EBI3 | 14287 | -0.084 | -0.4682 | No | ||
| 34 | IL18R1 | 14703 | -0.349 | -0.4865 | No | ||
| 35 | REL | 14913 | -0.486 | -0.4952 | No | ||
| 36 | SRC | 15241 | -0.705 | -0.5089 | No | ||
| 37 | IL12RB1 | 15346 | -0.770 | -0.5122 | No | ||
| 38 | IL1R1 | 15482 | -0.866 | -0.5168 | No | ||
| 39 | IL1B | 15675 | -1.000 | -0.5237 | No | ||
| 40 | TNF | 16079 | -1.307 | -0.5398 | No | ||
| 41 | RIPK2 | 16143 | -1.360 | -0.5401 | No | ||
| 42 | TRAF6 | 16980 | -2.105 | -0.5745 | No | ||
| 43 | TYK2 | 17095 | -2.213 | -0.5757 | No | ||
| 44 | MAPK9 | 17214 | -2.310 | -0.5768 | No | ||
| 45 | ERC1 | 17266 | -2.356 | -0.5748 | No | ||
| 46 | MAP3K14 | 17377 | -2.462 | -0.5753 | No | ||
| 47 | MAP2K6 | 17632 | -2.723 | -0.5819 | No | ||
| 48 | CHUK | 17643 | -2.730 | -0.5773 | No | ||
| 49 | MAPK14 | 17811 | -2.903 | -0.5796 | No | ||
| 50 | STAT4 | 17839 | -2.936 | -0.5755 | No | ||
| 51 | CD80 | 17952 | -3.058 | -0.5749 | No | ||
| 52 | BCL3 | 18305 | -3.430 | -0.5847 | Yes | ||
| 53 | IKBKG | 18397 | -3.530 | -0.5824 | Yes | ||
| 54 | SPHK2 | 18416 | -3.552 | -0.5767 | Yes | ||
| 55 | SYK | 18493 | -3.653 | -0.5734 | Yes | ||
| 56 | JAK2 | 18520 | -3.677 | -0.5678 | Yes | ||
| 57 | ATM | 18851 | -4.077 | -0.5754 | Yes | ||
| 58 | PRKCA | 18987 | -4.255 | -0.5738 | Yes | ||
| 59 | ARRB2 | 19063 | -4.371 | -0.5691 | Yes | ||
| 60 | FOS | 19178 | -4.546 | -0.5660 | Yes | ||
| 61 | IRF1 | 19214 | -4.601 | -0.5591 | Yes | ||
| 62 | STAT6 | 19356 | -4.818 | -0.5567 | Yes | ||
| 63 | CD3G | 19364 | -4.837 | -0.5481 | Yes | ||
| 64 | NFKB2 | 19492 | -5.020 | -0.5446 | Yes | ||
| 65 | BIRC2 | 19566 | -5.145 | -0.5385 | Yes | ||
| 66 | STAT5A | 19672 | -5.285 | -0.5336 | Yes | ||
| 67 | JAK1 | 19675 | -5.293 | -0.5239 | Yes | ||
| 68 | ATF2 | 19713 | -5.352 | -0.5157 | Yes | ||
| 69 | IKBKB | 19718 | -5.359 | -0.5060 | Yes | ||
| 70 | CYLD | 19870 | -5.610 | -0.5026 | Yes | ||
| 71 | PRF1 | 19877 | -5.627 | -0.4925 | Yes | ||
| 72 | CD3D | 19969 | -5.819 | -0.4860 | Yes | ||
| 73 | GATA3 | 20113 | -6.093 | -0.4813 | Yes | ||
| 74 | BCL10 | 20231 | -6.352 | -0.4749 | Yes | ||
| 75 | IL27RA | 20407 | -6.750 | -0.4705 | Yes | ||
| 76 | RELB | 20410 | -6.758 | -0.4581 | Yes | ||
| 77 | STAT2 | 20472 | -6.911 | -0.4482 | Yes | ||
| 78 | PIK3CA | 20532 | -7.036 | -0.4379 | Yes | ||
| 79 | FBXW11 | 20554 | -7.084 | -0.4258 | Yes | ||
| 80 | STAT3 | 20789 | -7.787 | -0.4222 | Yes | ||
| 81 | CD8B | 20855 | -7.998 | -0.4104 | Yes | ||
| 82 | TGFB1 | 20897 | -8.163 | -0.3973 | Yes | ||
| 83 | RELA | 21022 | -8.671 | -0.3869 | Yes | ||
| 84 | IL2RG | 21168 | -9.223 | -0.3766 | Yes | ||
| 85 | CD8A | 21185 | -9.290 | -0.3602 | Yes | ||
| 86 | CD4 | 21188 | -9.300 | -0.3431 | Yes | ||
| 87 | MAPK8 | 21208 | -9.408 | -0.3267 | Yes | ||
| 88 | SOCS1 | 21356 | -10.225 | -0.3146 | Yes | ||
| 89 | FRAP1 | 21383 | -10.384 | -0.2966 | Yes | ||
| 90 | GADD45B | 21406 | -10.572 | -0.2781 | Yes | ||
| 91 | CREBBP | 21411 | -10.605 | -0.2588 | Yes | ||
| 92 | TNFAIP3 | 21482 | -11.148 | -0.2414 | Yes | ||
| 93 | CD3E | 21545 | -11.647 | -0.2228 | Yes | ||
| 94 | STAT1 | 21656 | -13.091 | -0.2037 | Yes | ||
| 95 | TNFRSF1A | 21703 | -13.816 | -0.1804 | Yes | ||
| 96 | NFKBIA | 21775 | -15.114 | -0.1558 | Yes | ||
| 97 | LCK | 21778 | -15.166 | -0.1279 | Yes | ||
| 98 | CD247 | 21783 | -15.293 | -0.0999 | Yes | ||
| 99 | MALT1 | 21871 | -18.066 | -0.0706 | Yes | ||
| 100 | IL6ST | 21897 | -19.754 | -0.0353 | Yes | ||
| 101 | CD28 | 21902 | -20.380 | 0.0021 | Yes |
